Decoding
Target Druggability
Decoding
Path to New Therapies
Decoding
Target Druggability
Decoding
Path to New Therapies
Our Vision
Shifting the field from drug discovery to drug engineering
We believe that true acceleration of life-changing targeted medicines discovery will be achieved by decoding target druggability by small molecules in live cells
Our Vision
Shifting the field from drug discovery to drug engineering
We believe that true acceleration of life-changing targeted medicines discovery will be achieved by decoding target druggability by small molecules in live cells
Discover New Targets & Expand Druggable Proteome
Utilizing cutting-edge multi-proteomics and computational technologies, we have built and continue to expand a proprietary data bank and predictive models of small molecule interactions and modulation in live cells
iCLASS makes proteome-wide target ID, live-cell small molecule activity & target druggability data accessible to accelerate the development of better therapeutics
Discover New Targets &Expand Druggable Proteome
Utilizing cutting-edge multi-proteomics and computational technologies, we have built and continue to expand a proprietary data bank and predictive models of small molecule interactions and modulation in live cells
iCLASS makes proteome-wide target ID, live-cell small molecule activity & target druggability data accessible to accelerate the development of better therapeutics
Deeper Insights Every Day
Deeper Insights Every Day
Unlocking Targets and Sites inaccessible to mainstream discovery technologies
Operating in a native live cell environment, iCLASS unlocks molecular interactions that are otherwise challenging to identify using recombinant protein systems or structure-based techniques.
- Cryptic And Allosteric Sites
- Protein-Interaction Interfaces
- Multimeric Complexes
Unlocking Targets and Sites inaccessible to mainstream discovery technologies
Operating in a native live cell environment, iCLASS unlocks molecular interactions that are otherwise challenging to identify using recombinant protein systems or structure-based techniques.
- Cryptic And Allosteric Sites
- Protein-Interaction Interfaces
- Multimeric Complexes
Unlocking Live-Cell SAR & Proteome-Wide Selectivity Profiles
iCLASS improves success of discovery programs by ensuring (1) in vitro-to-in cellulo translation and (2) continuous off-target monitoring
With iCLASS, programs are advanced from chemistry with known proteome-wide target engagement profiles and live-cell SAR
Unlocking Live-Cell SAR &Proteome-Wide Selectivity Profiles
iCLASS improves success of discovery programs by ensuring (1) in vitro-to-in cellulo translation and (2) continuous off-target monitoring
With iCLASS, programs are advanced from chemistry with known proteome-wide target engagement profiles and live-cell SAR
Small molecule & therapeutic modality agnostic
We evaluate molecules in Live Cell Multi-Omics workflows to decode their proteome-wide profiles:
- Ligands & Modulators
- Inhibitors & Activators
- Degraders & Stabilizers
Small molecule &therapeutic modality agnostic
We evaluate molecules in Live Cell Multi-Omics workflows to decode their proteome-wide profiles:
- Ligands & Modulators
- Inhibitors & Activators
- Degraders & Stabilizers
iCLASS Exists For Global Impact
Our business model is designed with patients in mind. We make translatable data accessible to fuel the efforts of companies worldwide developing new therapies and therapeutic technologies. With no internal pipeline, our full focus is on the success of partners’ programs.
iCLASS Data Bank
Unlock instant access to the deepest target insights on flexible & cost-effective subscription plans
iCLASS Data Collaborations
Unlock limitless data analysis across disease areas, chemistry, targets and pocket classes through collaborations with our team.
iCLASS R&D Collaborations
Collaborate with us on a therapeutic target(s) program, disease area or target discovery projects to tap full iCLASS discovery platform capabilities from Target ID to PDC.
iCLASS Exists ForGlobal Impact
Our business model is designed with patients in mind. We make translatable data accessible to fuel the efforts of companies worldwide developing new therapies and therapeutic technologies. With no internal pipeline, our full focus is on the success of partners’ programs.
iCLASS Data Bank
Unlock instant access to the deepest target insights on flexible & cost-effective subscription plans
iCLASS Data Collaborations
Unlock limitless data analysis across disease areas, chemistry, targets and pocket classes through collaborations with our team.
iCLASS R&D Collaborations
Collaborate with us on a therapeutic target(s) program, disease area or target discovery projects to tap full iCLASS discovery platform capabilities from Target ID to PDC.
iCLASS Data Bank
Instant Access to Deepest Live Cell Target Druggability Insights
- Live-Cell Target And Target Site Interactions
- Site Scores
- Cryptic And Exo Ligandable Sites
- Molecular Profiles
- iCLASS – Enabled Sites And Targets
- Live-Cell SAR
iCLASSData Bank
Instant Access to Deepest Live Cell Target Druggability Insights
- Live-Cell Target And Target Site Interactions
- Site Scores
- Cryptic And Exo Ligandable Sites
- Molecular Profiles
- iCLASS – Enabled Sites And Targets
- Live-Cell SAR
